Andropause: what really happens to men after 40
Less energy, a growing belly, a quieter desire — and ads everywhere talking about "low testosterone" and "male menopause". It's easy to believe it all comes down to one hormone that you need to boost right away. The real picture is more honest and, fortunately, more hopeful.
It's not "male menopause"
In women, menopause happens to everyone and fairly abruptly. Men have nothing like that. Testosterone declines gradually and differently for everyone, and in healthy men it barely falls until around 70.
The main reason it drops in midlife isn't age itself but how the body is living: extra fat around the waist, diabetes, short sleep and sleep apnea, chronic stress, some medicines. That's why, for most men aged 40–60, "low testosterone" is a functional and reversible state, not a permanent breakdown.
Testosterone is more often a thermometer than a cause
This is the most important point. Low testosterone usually shows that the body is struggling; it doesn't cause the struggle by itself. Raise the number without touching the cause, and you usually don't feel better.
Only sexual signs are reliably linked to low testosterone — fewer morning erections, a quieter desire. And even that link is loose. Fatigue, low mood, "brain fog" and muscle loss barely tell low testosterone apart from short sleep, depression, extra weight or the thyroid. "Check your testosterone" questionnaires work no better than a coin toss.
A ring or watch doesn't measure or calculate testosterone. Heart rate, heart rate variability and "readiness" depend on dozens of things — from sleep to last night's drink. Treat them as a recovery signal, not as a "hormone level".
What brings you back into shape the most
Your waist. The most powerful lever. Fat around the waist lowers testosterone by itself, and losing 5–10% of your weight raises it roughly in proportion. Measuring your waist matters more than watching the scales.
Sleep. Short sleep and sleep apnea lower testosterone — and that's reversible. Apnea is very common in men over 40 and is almost always undiagnosed. Loud snoring with pauses and daytime sleepiness are a reason to discuss a sleep study with a doctor.
Strength training. It improves body composition, mood and desire. It doesn't raise resting testosterone — train for strength and metabolism, not for a "spike".
Less heavy drinking. Moderate drinking doesn't lower testosterone; heavy and binge drinking do, and that too is reversible.
The good news: fixing your metabolism improves how you feel and your desire, even if the testosterone number moves only a little.
What to avoid
- "Testosterone boosters". Almost none have evidence of benefit. Tribulus, D-aspartic acid, boron and DHEA don't raise testosterone. Some of these products contain undeclared drugs.
- "Low T" clinics and online prescriptions. They often prescribe the hormone to men with normal levels and don't ask about the heart or children.
- Testosterone "for yourself". Hormone from outside works almost like a male contraceptive: it suppresses sperm production, sometimes for a long time. If you still want children, this matters even more. Testosterone is prescribed only for a confirmed deficiency — after two morning tests and a doctor's decision.
When to see a doctor
- New erection problems at 40–60 — often an early signal from the blood vessels and heart, not just hormones. More in the article "Desire and erections after 40".
- Enlarged breast tissue.
- Changes in the testicles: smaller, softer, or a new lump.
- New headaches, worse vision at the edges, nipple discharge.
- Severe low mood. Any thoughts of harming yourself — get help from a professional or a crisis line right away.
What to try this week
- Measure your waist: aim for less than half your height.
- Get up at the same time all seven days.
- An evening without alcohol.
What this is based on
This article is based on topics from the VIA-L knowledge base. These are the published studies behind them:
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- Evaluation of Potential Hormonal Activities of Ashwagandha (Withania Somnifera) — Phytotherapy Research : PTR, 2025 doi
- Dietary Patterns and Testosterone Balance: A Review of Clinical Data and Perspectives — Journal of Advanced Research, 2025 doi
- Testosterone Treatment in Middle-Aged and Older Men with Hypogonadism — The New England Journal of Medicine, 2025 doi
- Semaglutide improved sperm morphology in obese men with type 2 diabetes mellitus and functional hypogonadism — Diabetes, Obesity & Metabolism, 2025 doi
- Effects of Testosterone Deficiency and Therapy on the Cardiometabolic Syndrome in Men — The American Journal of the Medical Sciences, 2025 doi
- The Effect of Chromium Supplementation on Cardio-Metabolic Risk Factors in Overweight and Obese Patients — Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS), 2025 doi
- Metabolic Effects of Testosterone Added to Intensive Lifestyle Intervention in Older Men With Obesity and Hypogonadism — The Journal of Clinical Endocrinology and Metabolism, 2025 doi
- Efficacy and Safety of Berberine on the Components of Metabolic Syndrome: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials — Frontiers in Pharmacology, 2025 doi
- Diagnosis and Treatment of Obstructive Sleep Apnea — JAMA Internal Medicine, 2025 doi
- Unraveling the Connection Between the Mediterranean Diet and Sleep Health: From Biological Mechanisms to Clinical Implications — Sleep & Breathing = Schlaf & Atmung, 2025 doi
- Magnesium Is a Key Trace Element in Obstructive Sleep Apnea: Evidence From Mendelian Randomization Analysis and NHANES Database — Respiratory Medicine, 2025 doi
- The Effects of L-Theanine Consumption on Sleep Outcomes: A Systematic Review and Meta-Analysis — Sleep Medicine Reviews, 2025 doi
- Efficacy of Incretin-Based Therapies in Obesity-Related Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis of Randomized Controlled Trials — Sleep Medicine Reviews, 2025 doi
- Examining the Effect of L-Theanine on Sleep: A Systematic Review of Dietary Supplementation Trials — Nutritional Neuroscience, 2025 doi
- The Effect of Mediterranean Diet and Chrononutrition on Sleep Quality: A Scoping Review — Nutrition Journal, 2025 doi
- Male Hypogonadism: Pathogenesis, Diagnosis, and Management — Diabetes & Endocrinology, 2024 doi
- Dietary Fat Quality and Serum Androgen Concentrations in Middle-Aged Men — European Journal of Clinical Nutrition, 2024 doi
- Do "Testosterone Boosters" Really Increase Serum Total Testosterone? A Systematic Review — International Journal of Impotence Research, 2024 doi
- Testosterone Treatment and Fractures in Men with Hypogonadism — The New England Journal of Medicine, 2024 doi
- Effect of Testosterone Replacement Therapy on Sexual Function and Hypogonadal Symptoms in Men With Hypogonadism — The Journal of Clinical Endocrinology and Metabolism, 2024 doi
- Depressive Syndromes in Men With Hypogonadism in the TRAVERSE Trial: Response to Testosterone-Replacement Therapy — The Journal of Clinical Endocrinology and Metabolism, 2024 doi
- Associations of Testosterone and Related Hormones With All-Cause and Cardiovascular Mortality and Incident Cardiovascular Disease in Men : Individual Participant Data Meta-Analyses — Annals of Internal Medicine, 2024 doi
- Effect of Testosterone on Progression From Prediabetes to Diabetes in Men With Hypogonadism: A Substudy of the TRAVERSE Randomized Clinical Trial — JAMA Internal Medicine, 2024 doi
- Chromium Supplementation and Type 2 Diabetes Mellitus: An Extensive Systematic Review — Environmental Geochemistry and Health, 2024 doi
- The Effect of Berberine Supplementation on Glycemic Control and Inflammatory Biomarkers in Metabolic Disorders: An Umbrella Meta-Analysis of Randomized Controlled Trials — Clinical Therapeutics, 2024 doi
- Intermittent Fasting and Health Outcomes: An Umbrella Review of Systematic Reviews and Meta-Analyses of Randomised Controlled Trials — EClinicalMedicine, 2024 doi
- Effectiveness of Stress Management Interventions to Change Cortisol Levels: A Systematic Review and Meta-Analysis — Psychoneuroendocrinology, 2024 doi
- Effects on Cardiovascular Risk Factors of a Low- Vs High-Glycemic Index Mediterranean Diet in High Cardiometabolic Risk Individuals: The MEDGI-Carb Study — European Journal of Clinical Nutrition, 2024 doi
- Effects of Various Exercise Types on Visceral Adipose Tissue in Individuals With Overweight and Obesity: A Systematic Review and Network Meta-Analysis of 84 Randomized Controlled Trials — Obesity Reviews : An Official Journal of the International Association for the Study of Obesity, 2024 doi
- Treatment of OSA and Its Impact on Cardiovascular Disease, Part 2: JACC State-of-the-Art Review — Journal of the American College of Cardiology, 2024 doi
- Sleep Disorders — NEJM Evidence, 2024 doi
- Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity — The New England Journal of Medicine, 2024 doi
- Exploring the Link Between Vitamin D Deficiency and Obstructive Sleep Apnea: A Comprehensive Review — Journal of Sleep Research, 2024 doi
- Prostate Safety Events During Testosterone Replacement Therapy in Men With Hypogonadism: A Randomized Clinical Trial — JAMA Network Open, 2023 doi
- Correlation Between Serum Zinc and Testosterone: A Systematic Review — Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS), 2023 doi
- Cardiovascular Safety of Testosterone-Replacement Therapy — The New England Journal of Medicine, 2023 doi
- The Effects of Sleep Deprivation and Obstructive Sleep Apnea Syndrome on Male Reproductive Function: A Multi-Arm Randomised Trial — Journal of Sleep Research, 2023 doi
- Exploring the Efficacy and Safety of a Novel Standardized Ashwagandha (Withania Somnifera) Root Extract (Witholytin®) in Adults Experiencing High Stress and Fatigue in a Randomized, Double-Blind, Placebo-Controlled Trial — Journal of Psychopharmacology (Oxford, England), 2023 doi
- Metabolic Syndrome and Erectile Dysfunction: A Systematic Review and Meta-Analysis Study — Journal of Endocrinological Investigation, 2023 doi
- Overall and Sex-Specific Effect of Berberine on Glycemic and Insulin-Related Traits: A Systematic Review and Meta-Analysis of Randomized Controlled Trials — The Journal of Nutrition, 2023 doi
- AASLD Practice Guidance on the Clinical Assessment and Management of Nonalcoholic Fatty Liver Disease — Hepatology (Baltimore, Md.), 2023 doi
- Obstructive Sleep Apnea and Serum Total Testosterone: A System Review and Meta-Analysis — Sleep & Breathing = Schlaf & Atmung, 2023 doi
- The Role of Magnesium in Sleep Health: A Systematic Review of Available Literature — Biological Trace Element Research, 2023 doi
- Sustained Improvements in the Cardiometabolic Profile of Patients With Obstructive Sleep Apnea After a Weight-Loss Mediterranean Diet/Lifestyle Intervention: 12-Month Follow-Up (6 Months Post-Intervention) of the "MIMOSA" Randomized Clinical Trial — Nutrition, Metabolism, and Cardiovascular Diseases : NMCD, 2023 doi
- Nutritional Modulation of Sleep Latency, Duration, and Efficiency: A Randomized, Repeated-Measures, Double-Blind Deception Study — Medicine and Science in Sports and Exercise, 2023 doi
- Sleep, testosterone and cortisol balance, and ageing men — Reviews in Endocrine & Metabolic Disorders, 2022 doi
- Aging and Androgens: Physiology and Clinical Implications — Reviews in Endocrine & Metabolic Disorders, 2022 doi
- Effects of Exercise Training on Anabolic and Catabolic Hormones with Advanced Age: A Systematic Review — Sports Medicine (Auckland, N.Z.), 2022 doi
- Nonpharmacological Interventions for the Management of Testosterone and Sperm Parameters: A Scoping Review — Clinical Therapeutics, 2022 doi
- Examining the Effects of Calorie Restriction on Testosterone Concentrations in Men: A Systematic Review and Meta-Analysis — Nutrition Reviews, 2022 doi
- Proposal for Standardizing Normal Insulin Ranges in Brazilian Patients and a New Classification of Metabolic Syndrome — Frontiers in Medicine, 2022 doi
- Effect of an Interdisciplinary Weight Loss and Lifestyle Intervention on Obstructive Sleep Apnea Severity: The INTERAPNEA Randomized Clinical Trial — JAMA Network Open, 2022 doi
- Association of Magnesium Intake With Sleep Duration and Sleep Quality: Findings From the CARDIA Study — Sleep, 2022 doi
- Dose-Response Relationship Between Weight Loss and Improvements in Obstructive Sleep Apnea Severity After a Diet/Lifestyle Interventions: Secondary Analyses of the "MIMOSA" Randomized Clinical Trial — Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine, 2022 doi
- Effect of Partial and Total Sleep Deprivation on Serum Testosterone in Healthy Males: A Systematic Review and Meta-Analysis — Sleep Medicine, 2021 doi
- Examining the Effects of Herbs on Testosterone Concentrations in Men: A Systematic Review — Advances in Nutrition (Bethesda, Md.), 2021 doi
- Sociodemographic, lifestyle and medical influences on serum testosterone and sex hormone–binding globulin in men from UK Biobank — Clinical Endocrinology, 2021 doi
- Testosterone and Exercise: Effects on Fitness, Body Composition, and Strength in Middle-to-Older Aged Men With Low-Normal Serum Testosterone Levels — Heart and Circulatory Physiology, 2021 doi
- Effects of Mediterranean Diet on Plasma Metabolites and Their Relationship With Insulin Resistance and Gut Microbiota Composition in a Crossover Randomized Clinical Trial — Clinical Nutrition (Edinburgh, Scotland), 2021 doi
- Effects of Dietary Eicosapentaenoic Acid and Docosahexaenoic Acid Supplementation on Metabolic Syndrome: A Systematic Review and Meta-Analysis of Data From 33 Randomized Controlled Trials — Clinical Nutrition (Edinburgh, Scotland), 2021 doi
- Management of Obesity in Cardiovascular Practice: JACC Focus Seminar — Journal of the American College of Cardiology, 2021 doi
- Obesity and Cardiovascular Disease: A Scientific Statement From the American Heart Association — Circulation, 2021 doi
- Optimal Threshold of Homeostasis Model Assessment of Insulin Resistance to Identify Metabolic Syndrome in a Chinese Population Aged 45 Years or Younger — Frontiers in Endocrinology, 2021 doi
- A Weight-Loss Mediterranean Diet/Lifestyle Intervention Ameliorates Inflammation and Oxidative Stress in Patients With Obstructive Sleep Apnea: Results of the "MIMOSA" Randomized Clinical Trial — European Journal of Nutrition, 2021 doi
- The Effectiveness of a Weight-Loss Mediterranean Diet/Lifestyle Intervention in the Management of Obstructive Sleep Apnea: Results of the "MIMOSA" Randomized Clinical Trial — Clinical Nutrition (Edinburgh, Scotland), 2021 doi
- Sleep Disordered Breathing and Cardiovascular Disease: JACC State-of-the-Art Review — Journal of the American College of Cardiology, 2021 doi
- Changes in cortisol levels by continuous positive airway pressure in patients with obstructive sleep apnoea: Meta‐analysis of 637 individuals — Clinical Endocrinology, 2021 doi
- Obstructive Sleep Apnea and Cardiovascular Disease: A Scientific Statement From the American Heart Association — Circulation, 2021 doi
- Reviewing the Evidence on Vitamin D Supplementation in the Management of Testosterone Status and Its Effects on Male Reproductive System (Testis and Prostate): Mechanistically Dazzling but Clinically Disappointing — Clinical Therapeutics, 2020 doi
- Age and Time-of-Day Differences in the Hypothalamo-Pituitary-Testicular, and Adrenal, Response to Total Overnight Sleep Deprivation — Sleep, 2020 doi
- The Association Between Popular Diets and Serum Testosterone Among Men in the United States — The Journal of Urology, 2020 doi
- A Randomized Controlled Pilot Trial of Sleep Health Education on Body Composition Changes Following 10 Weeks' Resistance Exercise — The Journal of Sports Medicine and Physical Fitness, 2020 doi
- Omega-3 Fatty Acids for the Primary and Secondary Prevention of Cardiovascular Disease — The Cochrane Database of Systematic Reviews, 2020 doi
- Colon-Delivered Short-Chain Fatty Acids Attenuate the Cortisol Response to Psychosocial Stress in Healthy Men: A Randomized, Placebo-Controlled Trial — Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology, 2020 doi
- Lipid Management in Patients With Endocrine Disorders: An Endocrine Society Clinical Practice Guideline — The Journal of Clinical Endocrinology and Metabolism, 2020 doi
- Diagnosis and Management of Obstructive Sleep Apnea: A Review — JAMA, 2020 doi
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- Influence of Dietary Sources of Melatonin on Sleep Quality: A Review — Journal of Food Science, 2020 doi
- Causal Link Between Vitamin D and Total Testosterone in Men: A Mendelian Randomization Analysis — The Journal of Clinical Endocrinology and Metabolism, 2019 doi
- A Clinical Perspective of Sleep and Andrological Health: Assessment, Treatment Considerations, and Future Research — The Journal of Clinical Endocrinology and Metabolism, 2019 doi
- Effects of different exercise training programs on body composition: A randomized control trial — Scandinavian Journal of Medicine & Science in Sports, 2019 doi
- Omega-3 Fatty Acids for the Management of Hypertriglyceridemia: A Science Advisory From the American Heart Association — Circulation, 2019 doi
- Associations Between Homeostasis Model Assessment (HOMA) and Routinely Examined Parameters in Individuals With Metabolic Syndrome — Physiological Research, 2019 doi
- Positional Therapy for Obstructive Sleep Apnoea — The Cochrane Database of Systematic Reviews, 2019 doi
- Clinical Use of the STOP-BANG Questionnaire to Determine Postoperative Risk in Veterans — The Laryngoscope, 2019 doi
- Psychotropic Effects of -Theanine and Its Clinical Properties: From the Management of Anxiety and Stress to a Potential Use in Schizophrenia — Pharmacological Research, 2019 doi
- Obstructive Sleep Apnea in Adults — The New England Journal of Medicine, 2019 doi
- Weight Loss and Lifestyle Interventions for Obstructive Sleep Apnoea in Adults: Systematic Review and Meta-Analysis — Obesity Reviews : An Official Journal of the International Association for the Study of Obesity, 2019 doi
- Effects of CPAP on Testosterone Levels in Patients With Obstructive Sleep Apnea: A Meta-Analysis Study — Frontiers in Endocrinology, 2019 doi
- Evaluation and Management of Testosterone Deficiency: AUA Guideline — The Journal of Urology, 2018 doi
- Testosterone Therapy in Men With Hypogonadism: An Endocrine Society Clinical Practice Guideline — The Journal of Clinical Endocrinology and Metabolism, 2018 doi
- Early Time-Restricted Feeding Improves Insulin Sensitivity, Blood Pressure, and Oxidative Stress Even Without Weight Loss in Men With Prediabetes — Cell Metabolism, 2018 doi
- Hypogonadotropic Hypogonadism in Men With Diabesity — Diabetes Care, 2018 doi
- Vitamin D and Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis — Sleep Medicine, 2018 doi
- The Role of Weight Management in the Treatment of Adult Obstructive Sleep Apnea — American Journal of Respiratory and Critical Care Medicine, 2018 doi
- Effect of Testosterone Treatment on Volumetric Bone Density and Strength in Older Men With Low Testosterone: A Controlled Clinical Trial — JAMA Internal Medicine, 2017 doi
- A Perspective on Middle-Aged and Older Men With Functional Hypogonadism: Focus on Holistic Management — The Journal of Clinical Endocrinology and Metabolism, 2017 doi
- Effect of Magnesium Supplementation on Insulin Resistance in Humans: A Systematic Review — Nutrition (Burbank, Los Angeles County, Calif.), 2017 doi
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- Clinical Practice Guideline for Diagnostic Testing for Adult Obstructive Sleep Apnea: An American Academy of Sleep Medicine Clinical Practice Guideline — Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine, 2017 doi
- Increased Physical Activity Has a Greater Effect Than Reduced Energy Intake on Lifestyle Modification-Induced Increases in Testosterone — Journal of Clinical Biochemistry and Nutrition, 2016 doi
- A Systematic Review and Meta-Analysis of Randomized Controlled Trials on the Effects of Magnesium Supplementation on Insulin Sensitivity and Glucose Control — Pharmacological Research, 2016 doi
- Effect of Magnesium Supplementation on Glucose Metabolism in People With or at Risk of Diabetes: A Systematic Review and Meta-Analysis of Double-Blind Randomized Controlled Trials — European Journal of Clinical Nutrition, 2016 doi
- Hypomagnesemia in Type 2 Diabetes: A Vicious Circle? — Diabetes, 2016 doi
- Physical Activity/Exercise and Diabetes: A Position Statement of the American Diabetes Association — Diabetes Care, 2016 doi
- Efficacy of Nasal Continuous Positive Airway Pressure on Patients With OSA With Erectile Dysfunction and Low Sex Hormone Levels — Respiratory Medicine, 2016 doi
- Sleep Apnoea and the Hypothalamic-Pituitary-Adrenal Axis in Men and Women: Effects of Continuous Positive Airway Pressure — The European Respiratory Journal, 2016 doi
- STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea — Chest, 2016 doi
- Vitamin D supplementation and testosterone concentrations in male human subjects — Clinical Endocrinology, 2015 doi
- Metabolic and hormonal effects of ‘catch‐up’ sleep in men with chronic, repetitive, lifestyle‐driven sleep restriction — Clinical Endocrinology, 2015 doi
- Nutrients other than carbohydrates: their effects on glucose homeostasis in humans — Diabetes/Metabolism Research and Reviews, 2015 doi
- Protective Effects of the Mediterranean Diet on Type 2 Diabetes and Metabolic Syndrome — The Journal of Nutrition, 2015 doi
- The Sleep-Promoting and Hypothermic Effects of Glycine Are Mediated by NMDA Receptors in the Suprachiasmatic Nucleus — Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology, 2015 doi
- Resistance Training Restores Muscle Sex Steroid Hormone Steroidogenesis in Older Men — FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2014 doi
- The Interplay between Magnesium and Testosterone in Modulating Physical Function in Men — International Journal of Endocrinology, 2014 doi
- The role of cherries in exercise and health — Scandinavian Journal of Medicine & Science in Sports, 2014 doi
- Efficacy of Continuous Positive Airway Pressure on Testosterone in Men With Obstructive Sleep Apnea: A Meta-Analysis — PloS One, 2014 doi
- Diagnosis of Obstructive Sleep Apnea in Adults: A Clinical Practice Guideline From theAmerican College of Physicians — Annals of Internal Medicine, 2014 doi
- Age-Associated Changes in Hypothalamic-Pituitary-Testicular Function in Middle-Aged and Older Men Are Modified by Weight Change and Lifestyle Factors: Longitudinal Results From the European Male Ageing Study — European Journal of Endocrinology, 2013 doi
- Melatonin ameliorates endothelial dysfunction, vascular inflammation, and systemic hypertension in rats with chronic intermittent hypoxia — Journal of Pineal Research, 2013 doi
- Restoring the Salivary Cortisol Awakening Response Through Nasal Continuous Positive Airway Pressure Therapy in Obstructive Sleep Apnea — Chronobiology International, 2013 doi
- Effect of Tart Cherry Juice (Prunus Cerasus) on Melatonin Levels and Enhanced Sleep Quality — European Journal of Nutrition, 2012 doi
- High STOP-Bang Score Indicates a High Probability of Obstructive Sleep Apnoea — British Journal of Anaesthesia, 2012 doi
- New Therapeutic Strategy for Amino Acid Medicine: Glycine Improves the Quality of Sleep — Journal of Pharmacological Sciences, 2012 doi
- Effects of Magnesium Supplementation on Testosterone Levels of Athletes and Sedentary Subjects at Rest and After Exhaustion — Biological Trace Element Research, 2011 doi
- The Effect of Mediterranean Diet on Metabolic Syndrome and Its Components: A Meta-Analysis of 50 Studies and 534,906 Individuals — Journal of the American College of Cardiology, 2011 doi
- Triglycerides and Cardiovascular Disease: A Scientific Statement From the American Heart Association — Circulation, 2011 doi
- Orexin Neurons Receive Glycinergic Innervations — PloS One, 2011 doi
- Testosterone Physiology in Resistance Exercise and Training: The Up-Stream Regulatory Elements — Sports Medicine (Auckland, N.Z.), 2010 doi
- Magnesium Effect on Testosterone-SHBG Association Studied by a Novel Molecular Chromatography Approach — Journal of Pharmaceutical and Biomedical Analysis, 2009 doi
- Multiple Biomarkers and Their Relative Contributions to Identifying Metabolic Syndrome — Clinica Chimica Acta; International Journal of Clinical Chemistry, 2009 doi
- Hypothalamic-Pituitary-Adrenal Axis Activation in Obstructive Sleep Apnea: The Effect of Continuous Positive Airway Pressure Therapy — The Journal of Clinical Endocrinology and Metabolism, 2009 doi
- Insulin Resistance, the Metabolic Syndrome, and Risk of Incident Cardiovascular Disease: A Population-Based Study — Journal of the American College of Cardiology, 2007 doi
- Neuroendocrine Dysfunction in Sleep Apnea: Reversal by Continuous Positive Airways Pressure Therapy — The Journal of Clinical Endocrinology and Metabolism, 1989 doi
The strength of this evidence varies: some are large reviews and meta-analyses, some are small single studies. The steps in the article are simple, low-risk self-care measures, not treatment, and they may not suit everyone.
This is general information, not a prescription. Tests and treatment are chosen by a doctor.