Desire and erections after 40: what men need to know
Desire comes less often. Erections aren't as reliable as they used to be. It's awkward to talk about even with a doctor, and many men quietly look for "something online". Yet this is one of those changes that says a lot about your health — and it responds well to help.
Desire
Desire is affected most by extra weight, short sleep and chronic stress. Testosterone plays a part too: fewer morning erections and a quieter desire are what's most reliably linked to it falling. But testosterone itself most often drops because of that same weight, sleep and stress.
Medicines matter too: some antidepressants, finasteride, spironolactone, opioids and some blood pressure tablets. Don't stop them on your own — discuss a switch with a doctor.
Erections — an early signal from the blood vessels
An erection depends on healthy blood vessels. The vessels of the penis are several times thinner than those of the heart, so the same vascular problem shows up here earlier — often 2–5 years before heart problems. It's not a verdict but a window: the body warns you in advance, while there's still a lot you can do.
Not everything is vascular. There are clues:
- more likely psychological — it started suddenly, it's "sometimes yes, sometimes no", morning erections are still there, against a background of stress and anxiety;
- more likely vascular — it came on gradually, in every situation, morning erections have gone, and there's a belly, high blood pressure or smoking.
Often it's a mix. Erection problems are quite often the first sign of diabetes: in about one in eight men.
What's worth checking with a doctor
Blood pressure, blood sugar (glucose or HbA1c), lipids and morning testosterone. It's inexpensive and shows a lot. Testosterone therapy raises desire but barely improves the erection itself — so checking the blood vessels matters more.
What helps — both blood vessels and erections
Aerobic exercise. The best-proven lever for erections specifically: walking, running, cycling, swimming — regularly.
Your waist. Losing weight helps; the effect builds over months.
Don't smoke. The strongest lever for the blood vessels.
A Mediterranean style. Berries, citrus fruit, olive oil, fish, whole grains.
Alcohol in moderation. Heavy and binge drinking harms erections; after quitting it's reversible.
The pelvic floor. Pelvic floor exercises are a useful addition.
Honestly: lifestyle works slowly, about a year or two. With a doctor, results come faster.
What to avoid — this matters for safety
- "Natural" potency products. Most of them secretly contain prescription erection drugs, sometimes at a higher dose than prescribed, and sometimes dangerous additives.
- Pills from the internet. Often fakes: the dose ranges from zero to double.
- Combining with nitrates. Erection medicines taken together with nitrates for angina (nitroglycerin and similar) cause a sharp drop in blood pressure — this is life-threatening. That's why a doctor prescribes these medicines after checking your heart.
Clinics actively sell shockwave therapy: there is an effect, but it's modest and not for everyone. Decide with a urologist, not by the ads.
When to see a doctor — urgently
- Erection problems together with chest pain or tightness, breathlessness or faintness during exertion — get your heart checked.
- A painful erection lasting more than 4 hours without arousal — this is an emergency.
- A curve, a firm lump or pain in the penis — see a urologist.
- A sudden, complete loss of erections.
- Together with numbness in the groin, weakness in the legs or problems urinating — urgently.
What to try this week
- Three 30-minute aerobic workouts — brisk walking counts.
- Measure your blood pressure at home two or three days in a row.
- Write down which medicines you take — for a talk with your doctor.
What this is based on
This article is based on topics from the VIA-L knowledge base. These are the published studies behind them:
- Erectile Dysfunction as an Early Biomarker of Cardiovascular Toxicity: Mechanisms and Clinical Implications — Microvascular Research, 2026 doi
- Associations Between Erectile Dysfunction, Low Testosterone, and Cardiometabolic Risk: An Age Stratified, Propensity-Matched Cohort Study — International Journal of Impotence Research, 2026 doi
- Erectile dysfunction and cardiovascular health — Urology, 2026 doi
- Efficacy of Lifestyle Interventions in Treating Erectile Dysfunction: A Systematic Review and Meta-Analysis of Randomized Controlled Trials — The Journal of Sexual Medicine, 2026 doi
- Low-Intensity Shockwave Therapy for Erectile Dysfunction: An Abridged Cochrane Review — BJU International, 2026 doi
- Testosterone and Bone Health in Men — Current Osteoporosis Reports, 2026 doi
- Hormonal Modulation With Withania Somnifera: Systematic Review and Meta-Analysis of Randomized-Controlled Trials — Planta Medica, 2026 doi
- Key Findings on the Efficacy and Safety of Testosterone Therapy From Two Large Randomized Trials — The Journal of Clinical Endocrinology and Metabolism, 2026 doi
- Metabolic Dysfunction–Associated Steatotic Liver Disease in Adults — JAMA, 2026 doi
- The Effect of Chromium Picolinate Supplementation on Cardiometabolic Biomarkers, Tumor Necrosis Factor-Α Gene Expression, and DNA Damage in Subjects With Metabolic Syndrome: A Randomized Placebo-Controlled Clinical Trial — Biological Trace Element Research, 2026 doi
- Do the Effects of Early Time-Restricted Eating Vary by Cardiometabolic Phenotype, Age, Sex, or Race? A Secondary Analysis of a Randomized Controlled Trial — The Journal of Nutrition, 2026 doi
- Efficacy of Exercise-Based Interventions for Metabolic Syndrome: An Umbrella Review With Meta-Analyses — Obesity Reviews : An Official Journal of the International Association for the Study of Obesity, 2026 doi
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- Low-Intensity Shockwave Therapy for Erectile Dysfunction — The Cochrane Database of Systematic Reviews, 2025 doi
- Associations Between Phosphodiesterase Type 5 Inhibitors and Vascular Function: A Systematic Review and Meta-Analysis on Randomized-Controlled Trials — Systematic Reviews, 2025 doi
- Safety of 12-Months Administration of Ashwagandha (Withania Somnifera) Standardized Root Extract in Healthy Adults: A Prospective, Observational Study — Phytotherapy Research : PTR, 2025 doi
- Evaluation of Potential Hormonal Activities of Ashwagandha (Withania Somnifera) — Phytotherapy Research : PTR, 2025 doi
- Dietary Patterns and Testosterone Balance: A Review of Clinical Data and Perspectives — Journal of Advanced Research, 2025 doi
- Testosterone Treatment in Middle-Aged and Older Men with Hypogonadism — The New England Journal of Medicine, 2025 doi
- Semaglutide improved sperm morphology in obese men with type 2 diabetes mellitus and functional hypogonadism — Diabetes, Obesity & Metabolism, 2025 doi
- Effects of Testosterone Deficiency and Therapy on the Cardiometabolic Syndrome in Men — The American Journal of the Medical Sciences, 2025 doi
- The Effect of Chromium Supplementation on Cardio-Metabolic Risk Factors in Overweight and Obese Patients — Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS), 2025 doi
- Metabolic Effects of Testosterone Added to Intensive Lifestyle Intervention in Older Men With Obesity and Hypogonadism — The Journal of Clinical Endocrinology and Metabolism, 2025 doi
- Efficacy and Safety of Berberine on the Components of Metabolic Syndrome: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials — Frontiers in Pharmacology, 2025 doi
- Testosterone Replacement in Men With Sexual Dysfunction — The Cochrane Database of Systematic Reviews, 2024 doi
- The Princeton IV Consensus Recommendations for the Management of Erectile Dysfunction and Cardiovascular Disease — Mayo Clinic Proceedings, 2024 doi
- Effect of Testosterone Replacement Therapy on Sexual Function and Hypogonadal Symptoms in Men With Hypogonadism — The Journal of Clinical Endocrinology and Metabolism, 2024 doi
- Male Hypogonadism: Pathogenesis, Diagnosis, and Management — Diabetes & Endocrinology, 2024 doi
- Dietary Fat Quality and Serum Androgen Concentrations in Middle-Aged Men — European Journal of Clinical Nutrition, 2024 doi
- Do "Testosterone Boosters" Really Increase Serum Total Testosterone? A Systematic Review — International Journal of Impotence Research, 2024 doi
- Testosterone Treatment and Fractures in Men with Hypogonadism — The New England Journal of Medicine, 2024 doi
- Depressive Syndromes in Men With Hypogonadism in the TRAVERSE Trial: Response to Testosterone-Replacement Therapy — The Journal of Clinical Endocrinology and Metabolism, 2024 doi
- Associations of Testosterone and Related Hormones With All-Cause and Cardiovascular Mortality and Incident Cardiovascular Disease in Men : Individual Participant Data Meta-Analyses — Annals of Internal Medicine, 2024 doi
- Effect of Testosterone on Progression From Prediabetes to Diabetes in Men With Hypogonadism: A Substudy of the TRAVERSE Randomized Clinical Trial — JAMA Internal Medicine, 2024 doi
- Chromium Supplementation and Type 2 Diabetes Mellitus: An Extensive Systematic Review — Environmental Geochemistry and Health, 2024 doi
- The Effect of Berberine Supplementation on Glycemic Control and Inflammatory Biomarkers in Metabolic Disorders: An Umbrella Meta-Analysis of Randomized Controlled Trials — Clinical Therapeutics, 2024 doi
- Intermittent Fasting and Health Outcomes: An Umbrella Review of Systematic Reviews and Meta-Analyses of Randomised Controlled Trials — EClinicalMedicine, 2024 doi
- Effectiveness of Stress Management Interventions to Change Cortisol Levels: A Systematic Review and Meta-Analysis — Psychoneuroendocrinology, 2024 doi
- Effects on Cardiovascular Risk Factors of a Low- Vs High-Glycemic Index Mediterranean Diet in High Cardiometabolic Risk Individuals: The MEDGI-Carb Study — European Journal of Clinical Nutrition, 2024 doi
- Effects of Various Exercise Types on Visceral Adipose Tissue in Individuals With Overweight and Obesity: A Systematic Review and Network Meta-Analysis of 84 Randomized Controlled Trials — Obesity Reviews : An Official Journal of the International Association for the Study of Obesity, 2024 doi
- Diagnostic Evaluation of Sexual Dysfunction in the Male Partner in the Setting of Infertility: A Committee Opinion — Fertility and Sterility, 2023 doi
- Prostate Safety Events During Testosterone Replacement Therapy in Men With Hypogonadism: A Randomized Clinical Trial — JAMA Network Open, 2023 doi
- Correlation Between Serum Zinc and Testosterone: A Systematic Review — Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS), 2023 doi
- Cardiovascular Safety of Testosterone-Replacement Therapy — The New England Journal of Medicine, 2023 doi
- The Effects of Sleep Deprivation and Obstructive Sleep Apnea Syndrome on Male Reproductive Function: A Multi-Arm Randomised Trial — Journal of Sleep Research, 2023 doi
- Exploring the Efficacy and Safety of a Novel Standardized Ashwagandha (Withania Somnifera) Root Extract (Witholytin®) in Adults Experiencing High Stress and Fatigue in a Randomized, Double-Blind, Placebo-Controlled Trial — Journal of Psychopharmacology (Oxford, England), 2023 doi
- Metabolic Syndrome and Erectile Dysfunction: A Systematic Review and Meta-Analysis Study — Journal of Endocrinological Investigation, 2023 doi
- Overall and Sex-Specific Effect of Berberine on Glycemic and Insulin-Related Traits: A Systematic Review and Meta-Analysis of Randomized Controlled Trials — The Journal of Nutrition, 2023 doi
- AASLD Practice Guidance on the Clinical Assessment and Management of Nonalcoholic Fatty Liver Disease — Hepatology (Baltimore, Md.), 2023 doi
- Interactions Between Erectile Dysfunction, Cardiovascular Disease and Cardiovascular Drugs — Cardiology, 2022 doi
- The Effect of Low-Intensity Shock Wave Therapy on Moderate Erectile Dysfunction: A Double-Blind, Randomized, Sham-Controlled Clinical Trial — The Journal of Urology, 2022 doi
- Sleep, testosterone and cortisol balance, and ageing men — Reviews in Endocrine & Metabolic Disorders, 2022 doi
- Aging and Androgens: Physiology and Clinical Implications — Reviews in Endocrine & Metabolic Disorders, 2022 doi
- Effects of Exercise Training on Anabolic and Catabolic Hormones with Advanced Age: A Systematic Review — Sports Medicine (Auckland, N.Z.), 2022 doi
- Nonpharmacological Interventions for the Management of Testosterone and Sperm Parameters: A Scoping Review — Clinical Therapeutics, 2022 doi
- Examining the Effects of Calorie Restriction on Testosterone Concentrations in Men: A Systematic Review and Meta-Analysis — Nutrition Reviews, 2022 doi
- Proposal for Standardizing Normal Insulin Ranges in Brazilian Patients and a New Classification of Metabolic Syndrome — Frontiers in Medicine, 2022 doi
- Penile low intensity shock wave treatment for PDE5I refractory erectile dysfunction: a randomized double-blind sham-controlled clinical trial — World Journal of Urology, 2021 doi
- 2021 ESC Guidelines on Cardiovascular Disease Prevention in Clinical Practice — 2021 doi
- Effect of Partial and Total Sleep Deprivation on Serum Testosterone in Healthy Males: A Systematic Review and Meta-Analysis — Sleep Medicine, 2021 doi
- Examining the Effects of Herbs on Testosterone Concentrations in Men: A Systematic Review — Advances in Nutrition (Bethesda, Md.), 2021 doi
- Sociodemographic, lifestyle and medical influences on serum testosterone and sex hormone–binding globulin in men from UK Biobank — Clinical Endocrinology, 2021 doi
- Testosterone and Exercise: Effects on Fitness, Body Composition, and Strength in Middle-to-Older Aged Men With Low-Normal Serum Testosterone Levels — Heart and Circulatory Physiology, 2021 doi
- Effects of Mediterranean Diet on Plasma Metabolites and Their Relationship With Insulin Resistance and Gut Microbiota Composition in a Crossover Randomized Clinical Trial — Clinical Nutrition (Edinburgh, Scotland), 2021 doi
- Effects of Dietary Eicosapentaenoic Acid and Docosahexaenoic Acid Supplementation on Metabolic Syndrome: A Systematic Review and Meta-Analysis of Data From 33 Randomized Controlled Trials — Clinical Nutrition (Edinburgh, Scotland), 2021 doi
- Management of Obesity in Cardiovascular Practice: JACC Focus Seminar — Journal of the American College of Cardiology, 2021 doi
- Obesity and Cardiovascular Disease: A Scientific Statement From the American Heart Association — Circulation, 2021 doi
- Optimal Threshold of Homeostasis Model Assessment of Insulin Resistance to Identify Metabolic Syndrome in a Chinese Population Aged 45 Years or Younger — Frontiers in Endocrinology, 2021 doi
- Association of Diet With Erectile Dysfunction Among Men in the Health Professionals Follow-up Study — JAMA Network Open, 2020 doi
- Lifestyles and sexuality in men and women: the gender perspective in sexual medicine — Reproductive Biology and Endocrinology : RB&E, 2020 doi
- Reviewing the Evidence on Vitamin D Supplementation in the Management of Testosterone Status and Its Effects on Male Reproductive System (Testis and Prostate): Mechanistically Dazzling but Clinically Disappointing — Clinical Therapeutics, 2020 doi
- Age and Time-of-Day Differences in the Hypothalamo-Pituitary-Testicular, and Adrenal, Response to Total Overnight Sleep Deprivation — Sleep, 2020 doi
- The Association Between Popular Diets and Serum Testosterone Among Men in the United States — The Journal of Urology, 2020 doi
- A Randomized Controlled Pilot Trial of Sleep Health Education on Body Composition Changes Following 10 Weeks' Resistance Exercise — The Journal of Sports Medicine and Physical Fitness, 2020 doi
- Omega-3 Fatty Acids for the Primary and Secondary Prevention of Cardiovascular Disease — The Cochrane Database of Systematic Reviews, 2020 doi
- Colon-Delivered Short-Chain Fatty Acids Attenuate the Cortisol Response to Psychosocial Stress in Healthy Men: A Randomized, Placebo-Controlled Trial — Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology, 2020 doi
- Lipid Management in Patients With Endocrine Disorders: An Endocrine Society Clinical Practice Guideline — The Journal of Clinical Endocrinology and Metabolism, 2020 doi
- Clinical studies on low intensity extracorporeal shockwave therapy for erectile dysfunction: a systematic review and meta-analysis of randomised controlled trials — International Journal of Impotence Research, 2019 doi
- Current guideline recommendations and analysis of evidence quality on low-intensity shockwave therapy for erectile dysfunction — International Journal of Impotence Research, 2019 doi
- Causal Link Between Vitamin D and Total Testosterone in Men: A Mendelian Randomization Analysis — The Journal of Clinical Endocrinology and Metabolism, 2019 doi
- A Clinical Perspective of Sleep and Andrological Health: Assessment, Treatment Considerations, and Future Research — The Journal of Clinical Endocrinology and Metabolism, 2019 doi
- Effects of different exercise training programs on body composition: A randomized control trial — Scandinavian Journal of Medicine & Science in Sports, 2019 doi
- Omega-3 Fatty Acids for the Management of Hypertriglyceridemia: A Science Advisory From the American Heart Association — Circulation, 2019 doi
- Associations Between Homeostasis Model Assessment (HOMA) and Routinely Examined Parameters in Individuals With Metabolic Syndrome — Physiological Research, 2019 doi
- Erectile Dysfunction: AUA Guideline — The Journal of Urology, 2018 doi
- Evaluation and Management of Testosterone Deficiency: AUA Guideline — The Journal of Urology, 2018 doi
- Testosterone Therapy in Men With Hypogonadism: An Endocrine Society Clinical Practice Guideline — The Journal of Clinical Endocrinology and Metabolism, 2018 doi
- Early Time-Restricted Feeding Improves Insulin Sensitivity, Blood Pressure, and Oxidative Stress Even Without Weight Loss in Men With Prediabetes — Cell Metabolism, 2018 doi
- Hypogonadotropic Hypogonadism in Men With Diabesity — Diabetes Care, 2018 doi
- Low-Intensity Extracorporeal Shock Wave Treatment Improves Erectile Function: A Systematic Review and Meta-Analysis — European Urology, 2017 doi
- Effect of Testosterone Treatment on Volumetric Bone Density and Strength in Older Men With Low Testosterone: A Controlled Clinical Trial — JAMA Internal Medicine, 2017 doi
- A Perspective on Middle-Aged and Older Men With Functional Hypogonadism: Focus on Holistic Management — The Journal of Clinical Endocrinology and Metabolism, 2017 doi
- Effect of Magnesium Supplementation on Insulin Resistance in Humans: A Systematic Review — Nutrition (Burbank, Los Angeles County, Calif.), 2017 doi
- Increased Physical Activity Has a Greater Effect Than Reduced Energy Intake on Lifestyle Modification-Induced Increases in Testosterone — Journal of Clinical Biochemistry and Nutrition, 2016 doi
- A Systematic Review and Meta-Analysis of Randomized Controlled Trials on the Effects of Magnesium Supplementation on Insulin Sensitivity and Glucose Control — Pharmacological Research, 2016 doi
- Effect of Magnesium Supplementation on Glucose Metabolism in People With or at Risk of Diabetes: A Systematic Review and Meta-Analysis of Double-Blind Randomized Controlled Trials — European Journal of Clinical Nutrition, 2016 doi
- Hypomagnesemia in Type 2 Diabetes: A Vicious Circle? — Diabetes, 2016 doi
- Physical Activity/Exercise and Diabetes: A Position Statement of the American Diabetes Association — Diabetes Care, 2016 doi
- Vitamin D supplementation and testosterone concentrations in male human subjects — Clinical Endocrinology, 2015 doi
- Metabolic and hormonal effects of ‘catch‐up’ sleep in men with chronic, repetitive, lifestyle‐driven sleep restriction — Clinical Endocrinology, 2015 doi
- Nutrients other than carbohydrates: their effects on glucose homeostasis in humans — Diabetes/Metabolism Research and Reviews, 2015 doi
- Protective Effects of the Mediterranean Diet on Type 2 Diabetes and Metabolic Syndrome — The Journal of Nutrition, 2015 doi
- Resistance Training Restores Muscle Sex Steroid Hormone Steroidogenesis in Older Men — FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2014 doi
- The Interplay between Magnesium and Testosterone in Modulating Physical Function in Men — International Journal of Endocrinology, 2014 doi
- Age-Associated Changes in Hypothalamic-Pituitary-Testicular Function in Middle-Aged and Older Men Are Modified by Weight Change and Lifestyle Factors: Longitudinal Results From the European Male Ageing Study — European Journal of Endocrinology, 2013 doi
- The Princeton III Consensus Recommendations for the Management of Erectile Dysfunction and Cardiovascular Disease — Mayo Clinic Proceedings, 2012 doi
- The Effect of Lifestyle Modification and Cardiovascular Risk Factor Reduction on Erectile Dysfunction: A Systematic Review and Meta-analysis — Archives of Internal Medicine, 2011 doi
- Effects of Magnesium Supplementation on Testosterone Levels of Athletes and Sedentary Subjects at Rest and After Exhaustion — Biological Trace Element Research, 2011 doi
- The Effect of Mediterranean Diet on Metabolic Syndrome and Its Components: A Meta-Analysis of 50 Studies and 534,906 Individuals — Journal of the American College of Cardiology, 2011 doi
- Triglycerides and Cardiovascular Disease: A Scientific Statement From the American Heart Association — Circulation, 2011 doi
- Testosterone Physiology in Resistance Exercise and Training: The Up-Stream Regulatory Elements — Sports Medicine (Auckland, N.Z.), 2010 doi
- Magnesium Effect on Testosterone-SHBG Association Studied by a Novel Molecular Chromatography Approach — Journal of Pharmaceutical and Biomedical Analysis, 2009 doi
- Multiple Biomarkers and Their Relative Contributions to Identifying Metabolic Syndrome — Clinica Chimica Acta; International Journal of Clinical Chemistry, 2009 doi
- Insulin Resistance, the Metabolic Syndrome, and Risk of Incident Cardiovascular Disease: A Population-Based Study — Journal of the American College of Cardiology, 2007 doi
The strength of this evidence varies: some are large reviews and meta-analyses, some are small single studies. The steps in the article are simple, low-risk self-care measures, not treatment, and they may not suit everyone.
This is general information, not a prescription. Tests and treatment are chosen by a doctor.